Andrew Churg Selected Research

Airway Remodeling

4/2016	Sex Differences in Airway Remodeling in a Mouse Model of Chronic Obstructive Pulmonary Disease.
1/2016	Sex-Related Differences in Pulmonary Function following 6 Months of Cigarette Exposure: Implications for Sexual Dimorphism in Mild COPD.
12/2014	Fibroblast signal transducer and activator of transcription 4 drives cigarette smoke-induced airway fibrosis.
12/2013	Club cell protein 16 and disease progression in chronic obstructive pulmonary disease.
1/2013	Aging does not enhance experimental cigarette smoke-induced COPD in the mouse.
1/2012	Late intervention with a myeloperoxidase inhibitor stops progression of experimental chronic obstructive pulmonary disease.
12/2011	Everything prevents emphysema: are animal models of cigarette smoke-induced chronic obstructive pulmonary disease any use?
12/2010	Animal models of cigarette smoke-induced chronic obstructive pulmonary disease.
2/2010	Modification of the rat airway explant transcriptome by cigarette smoke.
9/2009	Testing drugs in animal models of cigarette smoke-induced chronic obstructive pulmonary disease.

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Andrew Churg Research Topics

Disease

32	Mesothelioma 01/2022 - 01/2002
25	Chronic Obstructive Pulmonary Disease (COPD) 02/2020 - 06/2002
22	Malignant Mesothelioma 01/2022 - 03/2002
22	Emphysema 04/2016 - 09/2002
19	Airway Remodeling 04/2016 - 05/2003
18	Neoplasms (Cancer) 01/2022 - 01/2002
9	Pulmonary Hypertension 01/2012 - 10/2002
8	Inflammation (Inflammations) 01/2018 - 09/2002
8	Fibrosis (Cirrhosis) 12/2014 - 06/2002
7	Carcinoma (Carcinomatosis) 01/2021 - 08/2009
6	Lung Diseases (Lung Disease) 01/2022 - 05/2002
6	Adenocarcinoma 01/2021 - 03/2005
3	Interstitial Lung Diseases (Interstitial Lung Disease) 01/2022 - 11/2005
3	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2021 - 01/2017
3	Necrosis 01/2021 - 08/2007
3	Pleurisy (Pleuritis) 10/2012 - 03/2002
3	Chronic Bronchitis 12/2010 - 01/2007
2	Large Cell Carcinoma 01/2021 - 01/2020
2	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/2021 - 01/2020
2	Disease Progression 12/2013 - 09/2009
2	Lung Neoplasms (Lung Cancer) 08/2013 - 02/2007
2	Renal Cell Carcinoma (Grawitz Tumor) 05/2013 - 08/2009
2	Vascular Remodeling 01/2007 - 02/2006
2	Hyperplasia 10/2003 - 03/2002
1	Pheochromocytoma 01/2021
1	Peritoneal Neoplasms 01/2021
1	Lymphatic Metastasis 01/2021
1	Langerhans-Cell Histiocytosis (Histiocytosis, Langerhans Cell) 01/2020
1	Pleural Effusion (Pleural Effusions) 01/2020
1	Common Variable Immunodeficiency 01/2020
1	Weight Loss (Weight Reduction) 01/2020
1	Carcinogenesis 01/2019
1	HIV Infections (HIV Infection) 10/2018

Drug/Important Bio-Agent (IBA)

37	SmokeIBA 02/2020 - 05/2002
11	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 09/2009 - 09/2002
8	Proteins (Proteins, Gene)FDA Link 01/2022 - 03/2013
8	AsbestosIBA 06/2021 - 10/2003
6	Keratins (Keratin)IBA 01/2022 - 12/2011
6	Metalloproteases (Metalloproteinases)IBA 04/2008 - 09/2002
5	Coloring Agents (Dyes)IBA 01/2020 - 07/2014
4	Calbindin 2IBA 01/2021 - 03/2005
4	Claudin-4IBA 01/2021 - 11/2019
4	AntibodiesIBA 05/2013 - 03/2005
4	Peptide Hydrolases (Proteases)FDA Link 04/2008 - 09/2002
4	Serine (L-Serine)FDA Link 04/2008 - 10/2002
4	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 04/2008 - 10/2005
3	Coal (Coals)IBA 01/2022 - 01/2016
3	5'-methylthioadenosine phosphorylase (methylthioadenosine nucleosidase)IBA 11/2021 - 12/2018
3	Pancreatic Elastase (Elastase)IBA 03/2005 - 10/2002
3	Environmental Pollutants (Pollutants, Environmental)IBA 09/2003 - 12/2002
2	RNA (Ribonucleic Acid)IBA 01/2022 - 10/2018
2	AntigensIBA 01/2022 - 01/2018
2	ParaffinIBA 11/2020 - 01/2016
2	Gonadal Steroid Hormones (Sex Hormones)IBA 02/2020 - 04/2016
2	Indicators and Reagents (Reagents)IBA 01/2020 - 10/2012
2	Cyclin-Dependent Kinase Inhibitor p16IBA 01/2020 - 12/2018
2	Cyclin D1IBA 01/2020 - 01/2020
2	SteroidsIBA 04/2018 - 02/2006
2	Carrier Proteins (Binding Protein)IBA 09/2017 - 03/2013
2	Silicon Dioxide (Silica)FDA LinkGeneric 03/2016 - 10/2003
2	SilicatesIBA 03/2016 - 10/2003
2	CollagenIBA 12/2014 - 03/2005
2	Biomarkers (Surrogate Marker)IBA 12/2013 - 10/2012
2	Hematoxylin (Haematoxylon)IBA 03/2013 - 10/2012
2	Eosine Yellowish-(YS) (Eosin)IBA 03/2013 - 10/2012
2	Peroxidase (Myeloperoxidase)IBA 01/2012 - 03/2002
2	Pharmaceutical PreparationsIBA 03/2011 - 09/2009
2	AntioxidantsIBA 09/2009 - 04/2008
2	Protease Inhibitors (Protease Inhibitor)IBA 04/2008 - 03/2005
2	DesmosineIBA 08/2007 - 10/2002
2	Oxidants (Oxidizing Agents)IBA 01/2007 - 10/2003
2	Leukocyte Elastase (Neutrophil Elastase)IBA 01/2007 - 03/2005
2	Serine Proteases (Serine Protease)IBA 03/2005 - 04/2003
2	NF-kappa B (NF-kB)IBA 11/2003 - 09/2003
2	Particulate MatterIBA 10/2003 - 05/2003
2	MineralsIBA 10/2003 - 12/2002
2	Matrix Metalloproteinase 12IBA 04/2003 - 09/2002
1	UbiquitinIBA 01/2022
1	GastrinsIBA 01/2021
1	CatecholaminesIBA 01/2021
1	Sucrose (Saccharose)IBA 01/2021
1	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 11/2020
1	4- Acetamido- 4'- isothiocyanatostilbene- 2,2'- disulfonic Acid (SITS)IBA 11/2020
1	Formaldehyde (Formol)FDA Link 11/2020
1	DNA (Deoxyribonucleic Acid)IBA 11/2020
1	Immunoglobulin A (IgA)IBA 01/2020
1	B7-H1 AntigenIBA 01/2020
1	antineoplaston A10 (A 10)IBA 01/2020
1	1,1'- (4,4,7,7- tetramethyl- 4,7- diazaundecamethylene)bis- 4- (3- methyl- 2,3- dihydro(benzo- 1,3- thiazole)- 2- methylidene)quinolinium (TOTO)IBA 01/2020
1	xylometazoline (stas)IBA 08/2019
1	Immune Checkpoint InhibitorsIBA 01/2019
1	Neurofibromin 2 (Merlin)IBA 12/2018
1	Nuclear Proteins (Protein, Nuclear)IBA 12/2018
1	Tacrolimus (Prograf)FDA LinkGeneric 10/2018

Therapy/Procedure

7	Therapeutics 11/2016 - 01/2002
3	Drug Therapy (Chemotherapy) 01/2020 - 01/2002
1	Hyperthermic Intraperitoneal Chemotherapy 01/2021
1	Pneumonectomy (Lung Volume Reduction) 01/2020
1	Precision Medicine 11/2019
1	Contraindications 10/2018